2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N13356
    L-gamma-Glutamyl-L-threonine
    		99.97%
    L-gamma-Glutamyl-L-threonine (gamma-Glutamylthreonine; H-γ-Glu-Thr-OH; γ-Glu-Thr) is a dipeptide obtained through the formal condensation of the L-glutamic acid side chain carboxyl group and the L-threonine amino group. L-gamma-Glutamyl-L-threonine is present in high concentrations in human urine and exhibits antibacterial activity against Gram-negative bacterial. L-gamma-Glutamyl-L-threonine is also a flavor compound. Gamma-Glutamylthreonine is a metabolite catalyzed by γ-glutamyl transpeptidase and is associated with immune regulation. Gamma-Glutamylthreonine can be used in research on inflammation and bacterial infections.
    L-gamma-Glutamyl-L-threonine
  • HY-136498A
    T-705RMP ammonium
    T-705RMP (ammonium) is the ammonium form of T-705RMP. T-705RMP (ammonium)’s the inhibition of IMP dehydrogenase (IMPDH) activity is weak .
    T-705RMP ammonium
  • HY-N9484
    Menthofuran, 84%
    Menthofuran is a proximate toxic metabolite of (R)-(+)-Pulegone. Menthofuran regulates essential oil biosynthesis in peppermint by controlling a downstream monoterpene reductase.
    Menthofuran, 84%
  • HY-W278566
    Saluamine
    		99.90%
    Saluamine is an important N-dealkylated metabolite of Furosemide (HY-B0135) that is produced by microbial transformation and bile metabolism. Saluamine is a contaminant.
    Saluamine
  • HY-77101
    AP24592
    		99.34%
    AP24592 (M19) is an aromatic amine.
    AP24592
  • HY-130189R
    S-Phenylmercapturic acid (Standard)
    S-Phenylmercapturic acid (Standard) is the analytical standard of S-Phenylmercapturic acid. This product is intended for research and analytical applications. S-Phenylmercapturic acid, a metabolite of benzene, can be used as a biomarker, identified by GC, HPLC (UV or fluorescence detection), GC-MS, LC-MS/MS or immunoassay.
    S-Phenylmercapturic acid (Standard)
  • HY-126818
    Desfuroylceftiofur
    Desfuroylceftiofur is a metabolite of Ceftiofur (HY-N7102) and an Antibacterial agent. Desfuroylceftiofur exhibits comparable activity against Gram-negative bacteria to that of Ceftiofur.
    Desfuroylceftiofur
  • HY-117433S
    4-Hydroperoxy Cyclophosphamide-d4
    4-Hydroperoxy Cyclophosphamide-d4 is the deuterium labeled 4-Hydroperoxy cyclophosphamide. 4-Hydroperoxy cyclophosphamide is the active metabolite form of the proagent Cyclophosphamide. 4-Hydroperoxy cyclophosphamide crosslinks DNA and induces T cell apoptosis independent of death receptor activation, but activates mitochondrial death pathways through production of reactive oxygen species (ROS). 4-Hydroperoxy cyclophosphamide has the potential for lymphomas and autoimmune disorders.
    4-Hydroperoxy Cyclophosphamide-d<sub>4</sub>
  • HY-15876
    Clopidogrel thiolactone
    		98.0%
    Clopidogrel thiolactone is an important intermediate in the metabolism of Clopidogrel (HY-15283). Clopidogrel thiolactone has antiplatelet aggregatione effects. Clopidogrel is a P2Y12 receptor inhibitor that exerts antiplatelet effects.
    Clopidogrel thiolactone
  • HY-142122
    Imipramine N-oxide
    		99.90%
    Imipramine N-oxide is the metabolite of Imipramine. Imipramine N-oxide exhibits low toxicity in rat and mouse experiments. Imipramine N-oxide can be used for the research of endogenous depressions.
    Imipramine N-oxide
  • HY-100635
    Diacetolol
    Diacetolol is an active metabolite of the beta-adrenoceptor blocking agent Acebutolol (HY-17497).
    Diacetolol
  • HY-N7143R
    Monobutyl phthalate (Standard)
    Monobutyl phthalate (Standard) is the analytical standard of Monobutyl phthalate. This product is intended for research and analytical applications. Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant.
    Monobutyl phthalate (Standard)
  • HY-B0459
    Scopine
    		98.0%
    Scopine is a metabolite of Scopolamine (HY-N0296) and brain-targeting compound. Scopine significantly increases the brain exposure of Chlorambucil (HY-13593) and enhances its anti-glioma activity. Scopine can be used in targeted therapy research for brain gliomas.
    Scopine
  • HY-B0459A
    Scopine hydrochloride
    		99.69%
    Scopine hydrochloride is a metabolite of Scopolamine (HY-N0296) and brain-targeting compound. Scopine hydrochloride significantly increases the brain exposure of Chlorambucil (HY-13593) and enhances its anti-glioma activity. Scopine hydrochloride can be used in targeted therapy research for brain gliomas.
    Scopine hydrochloride
  • HY-133781
    cis-Clopidogrel-MP derivative
    cis-Clopidogrel-MP derivative (Clopidogrel-MP-AM) is a 3’-methoxyacetophenone derivative of Clopidogrel active metabolite. Clopidogrel is an orally active platelet inhibitor that targets P2Y12 receptor.
    cis-Clopidogrel-MP derivative
  • HY-126857
    5-Hydroxyomeprazole
    5-Hydroxyomeprazole (Hydroxyomeprazole) is a major metabolite of Omeprazole (HY-B0113) through catalysis by CYP2C19.
    5-Hydroxyomeprazole
  • HY-W103882
    2-(Benzhydrylsulfinyl)acetic acid
    		99.57%
    2-Benzhydrylsulfinylacetic acid (Modafinil acid) is the metabolite of modafinil.
    2-(Benzhydrylsulfinyl)acetic acid
  • HY-107856R
    5-Fluorouridine (Standard)
    5-Fluorouridine (Standard) is the analytical standard of 5-Fluorouridine. This product is intended for research and analytical applications. 5-Fluorouridine, a metabolite of5-Fluorouracil (HY-90006), is a potent ribozyme self-cleavage inhibitor. 5-Fluorouridine incorporates into both total and poly A RNA and has antiproliferative activity. 5-Fluorouridine induces apoptosis.
    5-Fluorouridine (Standard)
  • HY-131144S
    AMOZ-d5
    		99.0%
    AMOZ-d5 is a deuterium labeled AMOZ. AMOZ, a tissue bound metabolite of Furaltadone, Furaltadone is a synthetic nitrofuran antibiotic widely used.
    AMOZ-d<sub>5</sub>
  • HY-134039
    5-Hydroxy-8-methoxypsoralen
    		99.82%
    5-Hydroxy-8-methoxypsoralen (5-Hydroxyxanthotoxin) is a metabolite of Xanthotoxin. Xanthotoxin is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450), is an agent used to treat psoriasis, eczema, vitiligo and some cutaneous Lymphomas in conjunction with exposing the skin to sunlight.
    5-Hydroxy-8-methoxypsoralen
Cat. No. Product Name / Synonyms Application Reactivity